Long-term protective immune response elicited by vaccination with an expression genomic library of Toxoplasma gondii.
نویسندگان
چکیده
Immunization of BALB/c mice with an expression genomic library of Toxoplasma gondii induces a Th1-type immune response, with recognition of several T. gondii proteins (21 to 117 kDa) and long-term protective immunity against a lethal challenge. These results support further investigations to achieve a multicomponent anti-T. gondii DNA vaccine.
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عنوان ژورنال:
- Infection and immunity
دوره 71 9 شماره
صفحات -
تاریخ انتشار 2003